Both Serena and Venus Williams have had incredibly successful tennis careers, but Serena Williams is generally regarded as the more successful of the two. Serena has won more Grand Slam titles than Venus, with a total of 23 singles titles compared to Venus's 7. Additionally, Serena has spent more weeks ranked as the world No. 1 player and has achieved a Career Grand Slam in singles, winning each of the four major tournaments at least once. However, both sisters have made significant contributions to the sport and have left a lasting legacy in tennis history.